Tzyh-Chyuan Hour Selected Research

BPR1K653

1/2011

BPR1K653, a novel Aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells.

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Tzyh-Chyuan Hour Research Topics

Disease

21	Neoplasms (Cancer) 11/2023 - 08/2002
14	Prostatic Neoplasms (Prostate Cancer) 11/2023 - 05/2002
14	Carcinoma (Carcinomatosis) 01/2017 - 03/2002
7	Urinary Bladder Neoplasms (Bladder Cancer) 10/2014 - 10/2009
5	Leukemia 04/2011 - 04/2005
4	Carcinogenesis 04/2015 - 01/2006
3	Alzheimer Disease (Alzheimer's Disease) 08/2022 - 01/2022
3	Mouth Neoplasms (Oral Cancer) 01/2017 - 08/2010
3	Squamous Cell Carcinoma of Head and Neck 01/2017 - 06/2011
2	Disease Progression 08/2022 - 04/2013
2	Neoplasm Metastasis (Metastasis) 07/2022 - 11/2015
2	Reperfusion Injury 01/2013 - 12/2011
2	Renal Cell Carcinoma (Grawitz Tumor) 04/2012 - 09/2009
1	Esophageal Squamous Cell Carcinoma 07/2022
1	Inflammation (Inflammations) 01/2020
1	Endometriosis 12/2019
1	Pathologic Neovascularization 12/2019
1	Nasal Polyps (Nasal Polyp) 02/2015
1	Starvation 01/2015
1	Lymphatic Metastasis 07/2013
1	Margins of Excision 07/2013
1	7 Hereditary Prostate Cancer 07/2013
1	Genetic Predisposition to Disease (Genetic Predisposition) 03/2012
1	Erectile Dysfunction 03/2012
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 03/2012
1	Ischemia 12/2011

Drug/Important Bio-Agent (IBA)

13	Cisplatin (Platino)FDA LinkGeneric 01/2017 - 03/2002
8	Proteins (Proteins, Gene)FDA Link 08/2022 - 07/2009
5	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2020 - 02/2008
5	Paclitaxel (Taxol)FDA LinkGeneric 01/2017 - 09/2005
5	AndrogensIBA 04/2013 - 05/2002
4	Docetaxel (Taxotere)FDA Link 11/2023 - 04/2015
4	Biomarkers (Surrogate Marker)IBA 08/2022 - 06/2011
4	Arsenic Trioxide (Trisenox)FDA Link 08/2010 - 03/2002
3	ErbB Receptors (EGF Receptor)IBA 07/2023 - 03/2006
3	Gemcitabine FDA Link 01/2016 - 07/2011
3	ArsenicIBA 08/2010 - 03/2002
2	caffeic acid phenethyl esterIBA 07/2023 - 02/2022
2	Androgen Receptors (Androgen Receptor)IBA 02/2022 - 03/2008
2	Fluorouracil (Carac)FDA LinkGeneric 01/2017 - 05/2007
2	CCAAT-Enhancer-Binding Protein-deltaIBA 01/2017 - 08/2010
2	TriterpenesIBA 10/2014 - 03/2010
2	Ursolic AcidIBA 10/2014 - 10/2009
2	Ornithine Decarboxylase (Decarboxylase, Ornithine)IBA 04/2011 - 02/2008
2	Xanthine OxidaseIBA 12/2010 - 10/2009
2	Hormones (Hormone)IBA 03/2010 - 05/2007
2	AntioxidantsIBA 03/2010 - 09/2005
2	NF-kappa B (NF-kB)IBA 07/2008 - 05/2002
2	CurcuminIBA 02/2008 - 05/2002
2	VA 061 (VA061)IBA 03/2006 - 05/2002
1	TubulinIBA 11/2023
1	Protein Isoforms (Isoforms)IBA 11/2023
1	Blood Proteins (Serum Proteins)IBA 08/2022
1	Chlorogenic AcidIBA 07/2022
1	Propolis (Bee Bread)IBA 02/2022
1	Donepezil (Aricept)FDA LinkGeneric 01/2022
1	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 01/2022
1	Interleukin-10 ReceptorsIBA 12/2019
1	Interleukin-10 (Interleukin 10)IBA 12/2019
1	PlatinumIBA 01/2017
1	Cyclin D1IBA 01/2017
1	MicroRNAs (MicroRNA)IBA 01/2017
1	Transcription Factors (Transcription Factor)IBA 01/2017
1	Histone Deacetylase InhibitorsIBA 01/2016
1	trichostatin A (A 300)IBA 01/2016
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 11/2015
1	Indicators and Reagents (Reagents)IBA 02/2015
1	Green Fluorescent ProteinsIBA 02/2015
1	Amino Acids FDA Link 01/2015
1	3-methyladenineIBA 01/2015
1	ursaneIBA 10/2014
1	p38 Mitogen-Activated Protein KinasesIBA 07/2014
1	Insulin (Novolin)FDA Link 07/2013
1	Prostate-Specific Antigen (Semenogelase)IBA 07/2013
1	CalreticulinIBA 06/2013
1	methyl 4-azidophenylacetimidate (APAI)IBA 04/2013
1	Calcitriol Receptors (Calcitriol Receptor)IBA 04/2013
1	Heme Oxygenase-1IBA 01/2013
1	Estrogens (Estrogen)FDA Link 01/2013
1	Gonadal Steroid Hormones (Sex Hormones)IBA 01/2013
1	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 03/2012
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 03/2012
1	Caspase 3 (Caspase-3)IBA 01/2012
1	Genetic Markers (Genetic Marker)IBA 01/2012
1	Simvastatin (Zocor)FDA LinkGeneric 12/2011
1	AnthraquinonesIBA 09/2011
1	G(A1) ganglioside (GA(1))IBA 07/2011
1	AcidsIBA 07/2011
1	RNA (Ribonucleic Acid)IBA 07/2011
1	NucleosidesIBA 07/2011
1	Guanine Nucleotide Dissociation Inhibitors (GDIs)IBA 06/2011
1	hydroxydibenzoylmethaneIBA 04/2011
1	BPR1K653IBA 01/2011
1	Aurora KinasesIBA 01/2011

Therapy/Procedure

6	Drug Therapy (Chemotherapy) 11/2023 - 09/2009
6	Therapeutics 04/2013 - 09/2009
3	Castration 11/2023 - 04/2015
1	Combination Drug Therapy (Combination Chemotherapy) 01/2017
1	Nephroureterectomy 11/2015
1	Prostatectomy (Retropubic Prostatectomy) 07/2013